How much pineapple juice should I drink a day for inflammation?


Pineapple juice has become a popular dietary addition for many aiming to reduce inflammation. This sweet and tangy beverage contains beneficial enzymes called bromelain that have been shown to reduce inflammatory markers in the body. But how much pineapple juice should you drink each day to combat inflammation? Let’s take a closer look at the science behind pineapple juice and inflammation.

What is Inflammation?

Inflammation is the body’s natural response to injury or infection. It is characterized by redness, swelling, heat, and pain. Acute inflammation is a normal and healthy response that helps promote healing. However, when inflammation becomes chronic or lasts for long periods of time, it can cause damage and interfere with normal body functions. Chronic inflammation has been linked to various diseases and conditions like arthritis, heart disease, diabetes, cancer, and autoimmune disorders.

There are many potential causes and risk factors for chronic inflammation including:

Causes of Chronic Inflammation
Poor diet – high sugar, processed foods, trans fats, refined carbs
Food sensitivities
Gut imbalances like leaky gut
Lack of exercise
Chronic infections
Autoimmune conditions

Reducing chronic inflammation through diet and lifestyle changes may help lower risk for related health conditions.

Anti-Inflammatory Properties of Pineapple Juice

Pineapple is rich in nutrients, antioxidants, and enzymes that have potent anti-inflammatory effects in the body. Here are some of the key substances in pineapple juice that fight inflammation:


Bromelain refers to a group of digestive enzymes found in pineapples that help break down proteins. Multiple studies have found that bromelain helps reduce levels of certain inflammatory markers like IL-1β, IL-6, TNFα, and PGE-2 (1, 2). Bromelain may also help suppress activation of NF-kB, a protein complex involved in inflammation (3).

Vitamin C

Pineapples are packed with vitamin C, providing over 130% of the recommended daily value in just one cup. Vitamin C is a powerful antioxidant that can help counter inflammation by protecting against cellular damage from oxidative stress (4).


This trace mineral has critical anti-inflammatory and antioxidant functions in the body. Manganese is needed for the production of superoxide dismutase, a key enzyme that reduces inflammatory free radicals (5).


Pineapples contain good amounts of beta-carotene, a carotenoid antioxidant that gets converted to vitamin A in the body. Beta-carotene helps reduce inflammation by inhibiting the expression of certain pro-inflammatory cytokines (6).

Recommended Intake for Inflammation

So how much pineapple juice per day is ideal when trying to lower inflammation? Here are some general juice intake recommendations based on current research:

– 1-2 cups – This amount provides a good source of bromelain, vitamin C, manganese and other nutrients to help combat inflammation. Spread out intake throughout the day.

– 3-4 cups max – Higher amounts of juice may be beneficial for acute inflammation or short term use, but moderation is key. Too much sugar from the juice can be counterproductive.

– Empty stomach – Drink pineapple juice on an empty stomach about 30-60 minutes before meals. This allows bromelain concentrations to be higher for better anti-inflammatory effects.

– Fresh juice – Opt for fresh pineapple juice if possible for maximum enzyme levels. Bromelain content can diminish with storage over time.

– No sugar added – Avoid pineapple juice with added sugars which can contribute to inflammation. Look for unsweetened varieties.

Potential Side Effects

Pineapple juice is likely safe for most people when consumed in moderation. However, there are some potential side effects to be aware of:

– Digestive issues – Large amounts of pineapple juice may cause nausea, vomiting, diarrhea or stomach cramps due to the bromelain content.

– Allergies – Pineapple can cause food allergy symptoms like itching, hives, swelling or anaphylaxis in sensitive individuals. Discontinue use if any allergy symptoms develop.

– Drug interactions – Bromelain may interact with certain medications like antibiotics, anticoagulants, chemotherapy drugs and anti-platelet medications. Speak with a doctor if taking any prescription medications.

– High sugar – Excessive intake of the natural sugars in pineapple juice can spike blood sugar levels. This may be a concern for diabetics or pre-diabetics. Enjoy juice in moderation.

The Best Pineapple Juice Brands

Not all pineapple juices are created equal when it comes to nutrition, taste and low sugar content. Here are some of the top brands to look for:

Brand Details
Lakewood Pure pressed pineapple juice with no added sugar or preservatives
Dole 100% pineapple juice with 120mg of vitamin C per serving
Trader Joe’s Fresh-squeezed, no sugar added pineapple juice
Evolution Organic, not from concentrate pineapple juice
Daily Harvest Cold-pressed pineapple juice with ginger and lemon

When possible, look for juices labeled as “fresh”, “unsweetened” or “not from concentrate” to get maximum bromelain enzymes. Organic, cold-pressed and additive-free juices are also ideal.

Other Anti-Inflammatory Beverages

While pineapple juice can be effective, it’s also beneficial to include a variety of anti-inflammatory drinks in your diet. Some other options include:

– Tart cherry juice – Contains antioxidants called anthocyanins that reduce inflammation.

– Green tea – Polyphenols lower inflammatory markers CRP, IL-6 and TNFα.

– Ginger tea – Gingerol compounds in ginger tea inhibit inflammatory genes.

– Turmeric tea – Curcumin, the active compound in turmeric, has powerful anti-inflammatory properties.

– Kefir – A probiotic-rich beverage that can help improve gut health and immunity.

– Vegetable juice – Carrot, beet, spinach and other veggie juices provide antioxidants.

Pair these inflammation-fighting beverages with a balanced diet, exercise, stress management and proper sleep for optimal effects.


Pineapple juice contains beneficial enzymes and antioxidants that can help reduce inflammatory markers in the body when consumed in moderation. The bromelain in pineapple appears to be especially potent in decreasing inflammation. About 1-4 cups per day is recommended, ideally on an empty stomach and as part of a healthy diet and lifestyle. This amount can provide anti-inflammatory benefits without overdoing sugar intake. Be sure to choose unsweetened, fresh varieties free of additives. Include other antioxidant-rich beverages as well for maximum anti-inflammatory effects. Speak with a doctor if taking any medications, as bromelain can interact with some drugs. While more research is still needed, pineapple juice in moderation may be a tasty addition to an inflammation-fighting regimen.

Similar Posts

Leave a Reply

Your email address will not be published. Required fields are marked *