What fruit juices are anti-inflammatory?

Inflammation is the body’s natural response to injury or infection. It helps protect and heal damaged tissue. However, chronic inflammation that persists over time can lead to various health problems. Fortunately, certain fruits contain powerful antioxidants and compounds that can help fight inflammation.

Why Reduce Inflammation?

Inflammation is not inherently bad – it’s the body’s way of signaling the immune system to heal and repair damaged tissue. However, prolonged, chronic inflammation is linked to conditions like heart disease, diabetes, cancer, and autoimmune disorders.

Fruits and vegetables that contain antioxidants can combat excessive inflammation. Antioxidants protect cells from damage caused by unstable molecules called free radicals. When free radicals accumulate, they promote inflammation. Antioxidants neutralize free radicals, acting as natural anti-inflammatories.

Most Anti-Inflammatory Fruit Juices

Here are some of the top fruit juices loaded with antioxidants and anti-inflammatory compounds:

Tart Cherry Juice

Tart cherries contain high levels of anthocyanins, which give cherries their bright red color. Anthocyanins are potent antioxidants with anti-inflammatory effects. Studies show that drinking tart cherry juice can reduce markers of inflammation and relieve inflammatory joint and muscle pain.

Pomegranate Juice

Pomegranates are packed with polyphenol antioxidants linked to anti-inflammatory activity. Research indicates that drinking pomegranate juice may help lower inflammatory markers and ease joint pain and stiffness.

Blueberry Juice

Blueberries are rich in anthocyanins and other flavonoid antioxidants that reduce inflammation. Blueberry juice has been shown to decrease inflammatory cytokines and protect against inflammatory diseases.

Pineapple Juice

Pineapples contain the anti-inflammatory enzyme bromelain, which can help reduce swelling and joint pain. Drinking pineapple juice delivers anti-inflammatory bromelain throughout the body.

Orange Juice

Oranges are an excellent source of vitamin C, an antioxidant that fights inflammation. Orange juice also contains antioxidants like hesperidin and naringenin, which have anti-inflammatory properties.

Blackberry Juice

Blackberries are loaded with polyphenol antioxidants called anthocyanins that help protect the body from inflammation. Studies show blackberries decrease inflammatory markers.

Concord Grape Juice

Concord grapes and their juice are high in flavonoid antioxidants. Research demonstrates Concord grape juice can reduce inflammation and inflammatory signaling in the body.

Cranberry Juice

In addition to supporting urinary tract health, cranberries are rich in proanthocyanidins and vitamin C, which provide anti-inflammatory benefits. Cranberry juice has been shown to decrease inflammatory cytokines.

Plum Juice

Plums contain polyphenol antioxidants known as phenolic acids that have potent anti-inflammatory activities. Plum juice may protect against inflammation-related diseases.

Mango Juice

Mangos are high in vitamin A and vitamin C, antioxidants that can help lower inflammation. Mango juice’s anti-inflammatory effects may reduce chronic diseases caused by prolonged inflammation.

Anti-Inflammatory Compounds in Fruits

Certain compounds appear to be particularly powerful when it comes to fighting inflammation:


These antioxidant flavonoids give fruits like cherries and berries their vivid red-blue color. They inhibit inflammatory cytokines and protect cells from oxidative damage.

Vitamin C

This famous antioxidant plays a central role in immune health. It neutralizes free radicals that trigger inflammation and is required for collagen production.


This flavonoid antioxidant found in apples, grapes, and berries inhibits inflammatory pathways like NF-κB. It also blocks histamine release to reduce inflammation.


This polyphenol found in grapes, berries, plums, and peanuts reduces inflammatory markers. It also protects against oxidative stress and prevents inflammatory cytokine release.


This antioxidant carotenoid found in fruits like papayas, mangos, and oranges has powerful anti-inflammatory properties. It suppresses cytokine production and the COX-2 enzyme.

Choosing the Most Nutritious Juices

To get the most anti-inflammatory benefits from fruit juice, choose varieties that are:

  • 100% pure fruit juice with no added sugars
  • Minimally processed with no artificial ingredients
  • Rich in antioxidants like vitamin C and polyphenols
  • Made from darkly pigmented fruits like berries, cherries, and pomegranates

When possible, make your own fresh fruit juice at home. This will maximize the nutrient content compared to store-bought juices which may contain fewer anti-inflammatory antioxidants after processing.

Tips for an Anti-Inflammatory Diet

While fruit juice can be part of an anti-inflammatory diet, whole fruits and vegetables provide greater nutritional benefits. Here are some tips for following an anti-inflammatory diet:

  • Eat plenty of fruits and vegetables, especially deeply colored varieties like berries, leafy greens, tomatoes, and squash.
  • Choose whole grains like oats, quinoa, and brown rice over refined grains.
  • Eat fatty fish rich in omega-3s like salmon, sardines, and trout 2-3 times per week.
  • Use extra virgin olive oil as your primary cooking oil.
  • Limit processed foods, sugars, refined carbs, and saturated and trans fats.
  • Season foods with anti-inflammatory herbs and spices like ginger, turmeric, garlic, and rosemary.
  • Stay hydrated by drinking water throughout the day.

The Bottom Line

Chronic inflammation contributes to many diseases. The antioxidants and compounds found in fruits like tart cherries, citrus fruits, berries, grapes, and mangos have powerful anti-inflammatory properties. Drinking fruit juices made from these anti-inflammatory fruits can reduce inflammation for better health.

However, it’s ideal to get antioxidants from whole fruits and veggies whenever possible. An overall anti-inflammatory diet high in fruits, vegetables, healthy fats, and lean proteins can help keep inflammation in check.

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